Diagnosing Periodontal Disease

To date, the most widely accepted method for diagnosing periodontal disease or peri-implant status is based on clinical judgement after inspection of the gingival inflammation by observing bleeding upon probing of the target tissues and measuring the pocket depth. However, emerging trends in oral and periodontal diagnostic research are moving toward methods by which risk can be identified and quantified by objective measures, such as biochemical markers of disease or inflammation. The inflammatory response plays a fundamental role in oral surgery, being an essential process for repairing traumatized or infected tissues. This response can also serve as an early and objective means for monitoring health, by quantifying the biochemical markers of inflammation, even before clinical signs and symptoms are measurable. The repair of injury, and in particular the repair of a bone lesion around a dental implant, is a sequentially organized and coordinated mechanism of the body, wherein the inflammatory response is directed to remove damaged tissue and prepare the site for either regeneration or repair. Dental clinics in Turkey offer the most convenient and reliable implant treatments and much more… Since dental implants emerge from the bone toward the septic oral environment, the interactions between bacteria and host cells in the peri-implant tissues result in the release of several cytokines, depending on the nature of the bacterium and idiosyncratic host immune response. Several authors have found a close relationship between the degree of inflammation in peri-implant tissues and the various components collected from the peri-implant sulcus fluid (PISF), such as interleukin-1β, prostaglandin E2, matrix metalloproteinases, myeloperoxidase (MPO) and products of nitric oxide metabolism. In addition, the level of MPO has been shown to be a good indicator of neutrophil activity in failed periimplant sites as compared to successful endosseous dental implant sites. Thus, MPO may be a good marker of the inflammatory process and of implant failure. Some authors have suggested that MPO production is not confined to the inflamed sites, but also extends to sites that otherwise appear healthy. The toothless patients leave Dental clinics in Turkey happy and comfortable after having successful and reliable implant operations by the specialist dental surgeons… It is analyzed that the inflammatory response of the soft tissues surrounding dental implants subjected to several unfavorable conditions (ie, nonsubmerged implants inserted into fresh sockets, previously confirmed by trephine, with circumferential bone defects and without using membranes, in beagle dogs not receiving any measure of oral hygiene or soft diet). The rationale for this experimental design was to increase implant failure
rates in order to obtain an adequate subsample size for comparing the level of three highly robust inflammatory
mediators (MPO, TNF- α, and SOA) within the sites where implants were osseointegrated and those that were not. Both crestal and paracrestal biopsies of the gingiva were collected in order to test whether the inflammatory response might extend to the soft tissue of nearby regions, as has been reported elsewhere. To better understand why higher levels of certain biomarkers (mainly MPO but also TNF-α) might be elevated at sites where the implant failed in comparison with those sites where the implant survived, the main factors underlying the high failure rate and the high
peri-implant pocket depth of the surviving implants observed here should be reviewed. First, an increase in bone resorption in immediate implants in beagle dog studies has been demonstrated. In addition, the peri- implant defects created in fresh sockets generate higher marginal bone resorption. The ensuing inflammatory response of this additional trauma, added to the damage generated by the trephination per se, may be considered an additional risk factor leading to bone loss and periimplant inflammation. Furthermore, the flap elevation performed to carry out the trephination impairs the vascular supply to the healing site, in the initial phase of regeneration, hampering initial wound healing and possibly having a long-lasting effect on the dimensional reduction of the supporting bone and the concomitant inflammatory response. It also should be taken into account that the primary stability of implants was only assured by 3 mm of the apical zone of the implant, with the rest of the implant body contained within the circumferential defect. This caused the implants to have less than optimal primary stability to absorb the indirect occlusal loading exerted toward the healing abutments. Although there is no convincing causal relation between compression and bone loss, a clear relationship between high-stressed bones and bone resorption has been found. The surgeons at Dental clinics in Istanbul are highly experienced about implant operations and use the most reliable implant treatments technique with very high percentage of success to the toothless patients.

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About the Doctor

Dr. Özgür ÖZTÜRK, who was born in 1983 in İstanbul, completed his secondary education in Erzurum High School of Science. In 2002, he was accepted Çukurova University Faculty of Dentistry. A year after, he was transferred  to İstanbul University Faculty of Dentistry. After 5 year of education Öztürk, has succesfully  received the title of dentist. In the same year he started his doctorate in head of the department of  Oral and Maxillofacial Surgery at İstanbul University. Throughout his doctorate he participated lots of national and international congress, published scientific articles and posters.

In 2011, he studied Oral and Maxillofacial Surgery ,Tissue Engineering  in USA, Odontogenic treatments and Distraction Osteogenesis at Finland Oulu University. In the end of 2011, he accomplished his doctorate and become an expert about Oral and Maxillofacial Surgery. After doctorate, he completed his military service in Tatvan Military Hospital as Oral & Maxillofacial Surgent.

Dr. Öztürk is an active member of American Medical Association’’, ‘’Med Oral Patol Oral Cir Bucal’’, ‘’Norsk Oralmedisinsk Selskap’.

Dr. Özgür ÖZTÜRK

About the Doctor

Dr. Gizem Nur ÖZTÜRK, who was born in Edirne in 1988, started her education at  Edirne Anatolian Teacher Training School and was accepted to Faculty of Dentistry at İstanbul University in 2006. In 2010- 2011, she completed her education in Finland Oulu University and succeed in doctorate exam.

In 2011, she started her doctorate at İstanbul University Prosthetic Dental Treatment department. Throughout her doctorate, she published both national/international articles and posters.

Professional Interests: Aesthetic Dentistry, Ceramic Applications, Prothetic Treatments, Temporamandibular İlness.

Languages: English

Dr. Gizem Nur ÖZTÜRK

About the Doctor

Dr. Elif Nihan ATALAY, who was born in Eskisehir in year 1987, graduated from Adnan Menderes Anatolian High School in 2010 and was accepted to Faculty of Dentistry at Istanbul University. After completed her master degree Atalay, started her doctorate in Periodontology department at Bulent Ecevit University and graduated.

Professional Interests: Mukogingival surgery, Implant Applications

Languages: English

Dr. Elif Nihan ATALAY

About the Doctor

Dr. Madina GULVERDIYEVA, was born in Azerbaijan, graduated from Stomatology department at Azerbaijan Medical University. In 2016, she completed her doctorate in Prosthodontics Department at Gazi University. GULVERDIYEVA, attended lots of courses; Dental Smile Design, Mesotheraphy, Platelet Rich Plasma Therapy (PRP), Botulium Toxin Type-A in Facial Aesthetic Upper and Lower face indication , Hyaluronic Acid Derman Fillers in Facial Aesthetics. Throughout her education she published articles and posters.

Languages: Azerbaijani , Turkish, English, Russian


About the Doctor

Dt. Ayfer ATAMER, was born in Çorlu in year 1988, graduated from Faculty of Dentistry at İstanbul University. In 2013, she started her doctorate and continue her studies at the same faculty.

Professional Interests: Aesthetic dentistry, Temporomandibular joint disorders, Implant prosthetic treatments.

Dt. Ayfer ATAMER

About the Doctor

Dt. Muhammed KİŞİN, who was born in Idlib in year 1990, graduated from the Faculty of Dentistry at Kalamoon University in 2014. He also has DDS and DSD certificates.

Professional interests: Canal root treatment, dental fillings, aesthetic dentistry, surgical prosedures.

Languages: Arabic, Turkish, English

Dt. Muhammed KİŞİN

About the Doctor

Dt. Gizem HARMANKAYA, who was born in Ankara in year 1993, completed her secondary education at Ankara Hasan Ali Yücel Anatolian Teacher Training High School. In 2011 Harmankaya, accepted Faculty of Dentistry at Zonguldak Bülent Ecevit University. Also, she has TDB 24.International Dentistry Congress, Basic Implantology Course, Workshop and 4. Genç Edad Winter Symposium certificates.

Professional Interests: Dental fillings, canal root treatment, pediatric dentistry, aesthetic restoration, dental cleaning and polishing.

Languages: Turkish, English


About the Doctor

Dt. Batyr GULAMOV, was born in Turkmenia in year 1995. In 2012, he was accepted to Faculty of Dentistry at Belorussian State Medical University.

After graduated with success in 2017, GULAMOV, decided to work in Turkey and started to work in İmplant Akademi.

Professional Interest: Dental fillings, canal root treatment

Languages: Russian, English, Turkish